Analytical & Formulation Sciences, Protein Formulation Senior Scientist
Analytical & Formulation Sciences, Protein Formulation Senior Scientist
Analytical & Formulation Sciences, Protein Formulation Senior Scientist
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POSITION SUMMARY / MISSION
We are seeking an accomplished Senior Scientist to join our Analytical & Formulation Sciences team, specializing in the design and execution of formulation studies for protein therapeutics and new complex modalities in medical dermatology.
In this role, you will lead efforts to support developability assessment, early formulation development, and high-concentration formulation design for subcutaneous administration. Your expertise will be pivotal in evaluating and optimizing the stability, compatibility, and in-use performance of protein-based products. You will collaborate closely with analytical, process, and CMC teams to guide molecule selection and development, ensuring robust formulation strategies that advance our diverse dermatology portfolio. The ideal candidate will drive innovation in formulation sciences, mentor fellow scientists, and promote cross-functional experimental approaches to address emerging challenges of our diverse medical dermatology portfolio.
CORE RESPONSIBILITIES
Design, develop, and evaluate formulations for biologics (proteins, mRNA, complex modalities) across discovery and development stages.
Collaborate with CMC teams to ensure phase-appropriate formulation strategies.
Act as subject matter expert (SME) in internal technical governance, project reviews, and regulatory discussions, ensuring alignment between formulation approaches and broader CMC objectives.
Troubleshoot complex formulation challenges, proposing scientifically sound solutions to advance project objectives.
Conduct formulatability, formulability, and developability assessments, integrating physicochemical and biophysical data.
Develop high-concentration formulations suitable for subcutaneous administration and patient usability.
Perform protein stability studies (accelerated, stress, in-use, and long-term) and excipient compatibility evaluations.
Analyze data to establish structure-formulation-stability relationships.
Support technology transfer to CDMOs and contribute to technical documentation and regulatory packages.
Contribute to innovation initiatives in formulation technology and stability prediction.
Mentor junior scientists and help shape laboratory best practices and formulation workflows.
Initiate and lead collaborations with internal and external partners on new technologies and disease understanding, accelerating innovation and knowledge sharing.
REQUIRED EDUCATION AND EXPERIENCE
- PhD in Analytical Chemistry, Biochemistry, or a related scientific discipline.
- ≥5 years of relevant experience in biopharmaceutical analytical development (industry or academic translational research).
- Strong understanding of protein stability, biophysical characterization, and formulation science.
- Familiarity with developability assessments, excipient screening, and in-use stability.
- Experience in non-GxP research and early development environments preferred.
- Strong communication and collaboration skills in cross-functional R&D settings.
- Demonstrated ability to provide scientific leadership and strategic direction in cross-functional settings.
- Excellent problem-solving, communication, and mentoring skills.
- Experience interfacing with CMC, Regulatory, and external partners (CDMOs, CROs) desirable.
- Excellent written and verbal communication skills, with experience presenting at international scientific meetings.
PREFERRED SKILLS & COMPETENCES
- Hands-on experience with high-concentration formulation and subcutaneous delivery systems.
- Experience in formulation development for dermatological products is a strong plus.
- Strong organizational skills and meticulous attention to detail.
- Exceptional communication and leadership abilities, with a track record of mentoring and team-building.
- Demonstrated ability to lead technology collaborations and drive scientific innovation.
- Fluency in spoken and written English is essential, other languages are a plus.
Why work with Almirall?
We are a people-centric company where employees are at their best, patients and customer are at the heart of every decision, and our focus and agility allow us to deliver greater impact for all.
Additionally, for the 17th year in a row, we have been certified as Top Employer Spain, and also Top Employer Germany for the first time.
This strengthens our commitment to create a unique work environment that helps our employees to develop their skills to fullest and grow both professionally and as individuals.
We are delighted to have a great team that is proactive, innovative, and eager to transform the world of people with skin conditions.
We are proud of each one of our employees, their development, and growth: they are the success of the company.
Our purpose
"Transform the patients' world by helping them realize their hopes & dreams for a healthy life".
Our values
Care: we listen & empathize, we value diverse perspectives & backgrounds and we help each other succeed.
Courage: we challenge the status quo, we take full ownership and we learn from our success & failures.
Innovation: we put the patient and customer at the center, we create novel solutions and we empower entrepreneurial mindsets.
Simplicity: we act decisively and avoid over-analysis, we understand why before we act and we are agile & keep things simple.
At Almirall, it's all about people!
#wearealmirall
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